Clomiphene & Letrozole
The pills most often used first to trigger ovulation.
Medications
Fertility Medications
Understand commonly used fertility medications, how they work, possible side effects and questions to discuss with your clinician.
This section explains medication classes in general terms. It does not provide personal prescribing or dosing guidance. Always make medication decisions with a qualified prescriber, and never stop a medication suddenly without medical advice.
Medication classes
Explore by medication class
Gonadotropins
Hormone injections that stimulate the ovaries.
Trigger Shots
The injection that matures eggs and times ovulation.
Progesterone Support
Hormone support for the lining after ovulation or embryo transfer.
Metformin
An insulin-sensitizing medicine sometimes used in PCOS.
Prenatal Vitamins & Folic Acid
The one supplement nearly everyone trying to conceive should discuss.
Be prepared
Questions to ask before starting a medication
Bring these to your appointment. A good prescriber will welcome them.
- Why are you recommending this medication for me, and what are the alternatives, including no medication?
- How long will it take to work, and how will we know if it’s helping?
- What are the most common side effects, and which ones mean I should contact you?
- Does it interact with any other medications, supplements, alcohol or substances I use?
- Is it safe if I am pregnant, planning pregnancy or breastfeeding?
- How long might I need to take it, and how many cycles before we reconsider?
- What should I do if I miss a dose?
Find care
Talk to a clinician
Your OB/GYN, a fertility specialist or an online fertility program can discuss whether medication is appropriate for you.
Explore care options